Our scientific approch

Taylorsizer is a compact and automated biophysical characterization Analyzer using Taylor Dispersion Analysis which provides molecular size distribution, and viscosity and stability measurements.
Taylorsizer was developed to meet the needs of users from different fields such as Biotechnology, Health, or Food industry for example.
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Do you want a real size distribution of your Nanoparticles?

Nanoscale Metrix provides high precision technology to characterize and quantify species <50 nm.

Size & Purity Size Distribution by Taylor Dispersion Analysis (SD-TDA) allows to determine all the hydrodynamic diameter within complex compounds in their native state.

Stability Determination of Biomolecules Degradation or Aggregation using SD-TDA in kinetic studies. Our method provides fast high-throughput runs.

Coatings Measurement of nanoparticles sizes with and without coating. Growth control of the particle sizes during coating process and validation of coating quality with high resolution (<1 nm) by SD-TDA.

Ultra-Small Sizing made simple.

We offer an easy-to-use technology for resolutive size distribution requiring short method development time.
 

SIZE DISTRIBUTION
Taylor Dispersion Analysis (SD-TDA) ranges from molecular sizes (0.5 nm) to 400 nm Hydrodynamic Diameter of nanoparticles and allows the size measurement in a single run of native protein/particle and related degradation products or aggregates.
 
FAST ANALYSIS TIME
Taylorsizer is an automated biophysical characterization tool using Taylor Dispersion Analysis which provides molecular size distribution, and viscosity and stabililty measurements.
 
MULTI-DETECTOR
Taylorsizer standard confirguration is provided with a UV-Visible detection (190-650 nm or 190-1010 nm) offering Size Distribution measurements that are not affected by the presence of aggregates. The Diode Array Detector can, in addition, measure the UV Absorbance spectrum of the solution.

A LASER-INDUCED FLUORESCENCE DETECTOR
It can be added as an option to the Taylorsizer for the detection of labelled-biomolecules or nanoparticles in complex matrices.
 
LOW SAMPLE AMOUNT CONSUMPTION
Only few nL of sample are mandatory to run Size Distribution – Taylor Distribution Analysis (SD-TDA). Sample can be injected without dilution (native conditions)
 
LARGE TEMPERATURE RANGE
The temperature control of sample storage (5 – 55°C) and measurement chamber (15-55°C) temperatures guarantees good accuracy and reproducibility of size and viscosity measurements.
 
HIGH PERFORMANCES IN SIZE DISTRIBUTION
Improved resolution through a powerful patented algorithm for ultrasmall and small nanoparticles size distribution.

TaylorSizer Plateform
Our software contains a unique algorithm based on a patent from Montpellier University.

•    Taylorsizer is provided with a simple software interface
for the control of the measurement platform and the data analysis.
•    The relative quantification of each subpopulation and the PDI is directly provided by SD-TDA software at the end of the analysis.
•    Data are displayed by the software as tables,
SD-TDA plots, and Taylorgram real time monitoring during the measurement.
•    Data Analysis is carried out by a patented algorithm
allowing the Size Distribution computing from an experimental Taylorgram.
•    Software also includes two specific tools :
A tool for viscosity measurement and one for assistance to method development using abacuses as described by Taylor.